Synthesis and properties of novel and biologically important polyaza heterocycles, tandem cascade chemistry, applications of the Pummerer reaction for heterocyclic synthesis, alkaloid chemistry and the cyclization reactions of metallo carbenoids for organic synthesis.

Total synthesis and development of new reaction methods.

Total synthesis of biologically active natural products and structural analogues, molecular modelling, and discovery and development of new synthetic methods with particular interest in asymmetric reactions.

Organic synthesis, bioorganic chemistry, medicinal chemistry and chemical biology.

Synthesis of inhibitors of neutral-sphingomyelinase, telomerase, helicase and inhibitors of other biological mechanisms that are important to human health and the treatment of disease.

Functional genomics and proteomics, cell biology, virology, signal transduction, molecular mechanisms, chemical synthesis.

Total synthesis of cytotoxic marine and microbial natural products.

Synthesis of enamide and related natural products, synthesis of natural and unnatural epoxyquinoids, parallel synthesis and combinatorial chemistry.

Synthetic methodology, vitamin D analogs, antimalarial peroxide drugs.