Development of new synthetic methods and strategies, and their application in the total synthesis of natural products and biologically important compounds.

Development of novel asymmetric transformations and concepts. Total synthesis of natural products of biological significance. Design of unique supramolecular architectures. Medicinal chemistry. Chemical genomics and enantioselective recognition processes.

Glycoprocessing enzyme inhibition and mechanism. Exploring enzyme systems. Novel drug delivery systems. Synthesis and use of glycoproteins. Glycoside and oligosaccharide synthesis.

Development of new methods for chiral synthesis of biological active compounds.

Research into the bio-organic chemistry of nucleic acids. Including molecular recognition of DNA by small molecules and the design of artificial transcriptional activators.

Supramolecular and dendrimer chemistry. Modern medicinal chemistry. Advanced materials based on carbon-rich acetylenic molecular architecture. Synthetic fullerene chemistry.

Study of the reactivity of free radicals and other reactive fluoroorganic compounds.

Asymmetric synthesis and the application of stereoselectve oxidation and reduction reactions to total synthesis.

Devise, develop, and apply new ideas in organic chemistry to the efficient synthesis of interesting molecules, particularly natural products with medicinal applications.