Chemistry of natural products. Phytochemistry of medicinal plants. Pharmacognosy.

Development of new catalytic processes for asymmetric synthesis. Development of new methodology and its applications in synthesis. Total synthesis of biologically important targets.

Conformational rigidification in nucleic acid mimics. Development of functionalized polyamines for the molecular recognition of folded RNA. Reactivation of mutant p53 with small organic molecules.

Development of new synthetic techniques, total synthesis, and the study of peptidomimetics.

Functional Genomics through chemical and biological diversity. Synthesis and evaluation of natural products that we believe have RNA as their primary cellular target.