Alpha Gel Fox
Features two methods of molecular weights and pI determination, automatic or semi-automatic matching spots between gels, and several data tables.
CAROL
Offers point-pattern-matching for the analysis of 2D gel images. Java client application can be used directly from an internet browser or can be downloaded. Interfaces with the gelmatching server via the internet.
Delta2D & Protecs
Produce dual channel images of 2D gels from different experiments or samples to show differences and similarities between two gels. Runs on Windows, Macintosh, and Linux.
GELLAB II+
2D gel analysis software for Windows. Scanalytics Inc. also offers Gene Profiler, 1Dscan EX, and DNAscan for Windows and ONE-Dscan for Macintosh.
GelScape
A free, platform-independent program to analyzing standard 1D and 2D protein gels. Users can calculate spot intensity, prepare HTML image maps and archive annotated gels to a public database using a standard web browser interface.
ImageMaster 2D Platinum & DeCyder
http://www5.amershambiosciences.com/APTRIX/upp00919.nsf/Content/Proteomics+In+Expression+Analysis+Ar
ImageMaster 2D Platinum has scripting tools to facilitate automated gel analysis and is powered by Melanie. Decyder was made specifically for 2D DIGE analysis.
Impressionist
Analyzes the quality of proteomics data and lets you set quality parameters to ensure data reliability throughout your experiments. Is easily installed on a server so that data from 2D gel experiments can be accessed on your Intranet using a web browser.
Investigator HT Analyzer
2D gel analysis software that can provide data to an Investigator ProPic robotic workstation for protein excision. HT Analyzer Evolution works with HT Analyzer to enable batch processing for higher throughput analysis.
Melanie
Analyzes, annotates, and queries 2D gel samples for DNA and proteomic applications. Has recently been acquired by Amersham Biosciences and incorporated into ImageMaster 2D Platinum.
NCI Flicker
A Java applet which reads two images from the Internet and then displays them in the your Web browser. It allows you to enhance them in various ways and to compare them visually in a third window called the flicker window.
Open2Dprot
Open source quantitative proteomics database software for data mining and analysis of 2D gels. Will be based on the Unix version of the NCI GELLAB-II image analysis software.
PDQuest
A 2D gel analysis software from Bio-Rad. Features a proprietary SYPRO Ruby filter, which allows auto-recognition and removal of background speckles, as well as gaussian modeling, which is used to help eliminate the need for manual editing.
Progenesis & Phoretix
High-level 2D gel analysis software that aims to be fully automate analyses. The INCA algorithm reduces noise prior to spot detection.
Proteomweaver
Gel analysis software that uses a step-by-step wizard to guide users through an analysis. Also features the concept of "super-spots" to connect matched spots in different gels and perform a database-wide comparison of spot expression levels changes.
Proteoscope
Fully featured and automated 2D gel analysis software for Windows.
TotalLab
Software for 1-D and 2-D densitometry of gel patterns, blots, microtitre plates and colony counting.
Z3 & Z4000
Uses a proprietary process that reverses the customary order of the analysis steps. First the images are registered, then spots are identified, quantified, annotated, archived and published.