Large scale ENU based mouse mutagenesis for developmental defects

The mouse core facility at Boston University School of Medicine provides centralized, expert service to produce successfully transgenic as well as knock out mice for investigators at Boston University and as an outside service.

The CGDN Core Facility offers investigators with efficiency and quality in transgenic and knock-out mouse technologies.

Centre for Modeling Human Disease (CMHD) use genome-wide ENU based random mutagenesis in mice to discover new genes and create new mouse models.

An updated list of all available Cre transgenic mice alongwith contact addresses.

Provide a full range of services for the production, characterization and analysis of transgenic and gene-targeted mice, to both the Emory community as well as to external entities.

A non-profit repository for the collection, archiving and distribution of relevant mutant strains essential for basic biomedical research.

The German Genetrap Consortium (GGTC) generates a reference library of gene trap sequence tags (GTST) from insertional mutations generated in mouse embryonic stem (ES) cells.

ENU-Mouse Mutagenesis Screen in the German Human Genome Project

A large scale mouse genetics programme to identify new phenotypes of relevance to human disease through ENU mutagenesis.

The Facility produces transgenic mice by microinjecting investigator-provided DNA into fertilized mouse eggs and chimeric mice by microinjecting embryonic stem (ES) cells into mouse blastocysts.

Gene targeting laboratory at The John Curtin School of medical research, Australian National University.

The Transgenic and Gene-targeting Institutional Facility (TGIF) at the University of Kansas Medical Center (KUMC) provides a centralized facility for production of transgenic mice.

MCDB Transgenic Facility,University of Colorado, Boulder, CO.

Not-for-profit mouse mutagenesis program.

Services include transgenic mouse production by microinjection of oocytes, gene targeting in ES cells, generation of ES cell chimeras, and embryo cryopreservation.

Core transgenic mouse research facility at the Medical University of South Carolina. Directly involved in skin and hair development research.

The institutional Mouse Genetics Research Facility has been established to provide the Mount Sinai research community with access to state-of-the-art facilities for the production of transgenic and knockout mice.

Collection of several hundred mouse stocks, most of which propagate mutations induced by radiations or chemicals in various stages of male or female gametogenesis.

Serves as a centralized resource for the production of transgenic and gene-targeted mice for Purdue investigators.

A large scale mouse ENU mutagenesis project at Riken GSC, Japan.

A core facility that would produce transgenic and knockout mice for the researchers at St. Jude Children's Research Hospital (SJCRH).

Consult and conduct transgenic (pronuclear DNA injection) and gene-targeting projects in mice.

The Consortium's purpose is to promote mouse models for human genetic diseases and as subjects for the study of gene function.

Sequence information for Cre/lox vectors used for DNA targeting and to generate conditional knockout and gene activation cassettes in transgenic and gene knockout mice.

The Embryonic Stem Cell Core has been created to help create mutations in murine embryonic stem cells. The core has several missions, including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation.

Provide transgenic, targeting, targeted point mutations, chimera, rederivation and cryopreservation services for the Cleveland Biomedical Research Community. Includes mouse breeding FAQs, costs, and protocols.

A central information resource on NIH's trans-NIH mouse initiative.

Service run by the University of Queensland's Institute for Molecular Biosciences which provides transgenic mice and other related services for Australian Science.

Links to useful transgenic resources

At the Harvard Skin Disease Research Center. Mainly provides services for the generation of mouse skin disease models.

The Tufts-New England Medical Center and Tufts University School of Medicine Transgenic Core Facility (TCF) is a fee-for-service facility.

Transgenic histopathology laboratory at the University of California-Davis providing comprehensive light and electron microscopic analysis of tissues submitted by interested investigators .

Home Page of the Transgenic Mouse Facility at UC-Irvine. The TMF is a core facility serving the UCI community, other UC campuses, and outside collaborators of UC researchers.

University of Colorado Health Sciences Center. Transgenic Mouse Core Laboratory.

The transgenic mouse facility will make transgenic mice for investigators at UCLA by microinjection of DNA into fertilized mouse eggs. It will also create gene knock out mice by injection of engineered ES cells into blastocysts.

The Transgenic Mouse and Embryonic Stem Cell Gene Targeting Core is a state-of-the-art facility that has an outstanding track record in the production of genetically altered mice.

The primary purpose of the Transgenic/Targeted Mutagenesis Shared Resource facility is to provide microinjection services for investigators interested in generating mutant mice.

University of Florida Shands Cancer Center. Transgenic Mouse Core Facility.

The University of Miami Transgenic and Targeted Mutant Mouse Core Facility is subsidized by the Sylvester Comprehensive Cancer Center. The primary objective of the facility is to efficiently produce transgenic mice and targeted-mutant mice

The mission of the Transgenic-Knockout Animal Core Facility is to produce genetically-altered mice for the UMASS Medical School Community.

University of North Carolina at Chapel Hill. The Facility makes animal models of human disease for medical researchers by creating genetically modified mice. Transgenic and gene-targeted animals are generated from DNA constructs provided by clients.

News release that was reported in the journal nature concerning the first reproducible cloning of mammals from adult cells.

The facility provides state-of-the-art equipment and expertise essential for producing transgenics and maintains a mouse colony.

The Transgenic Core routinely prepares transgenic mice and mice with targeted mutations for University of Michigan investigators.

University of Missouri-Columbia Transgenic Animal Core

The Laboratory for Developmental Biology is a shared service support facility of the Institute in which embryonic stem cell lines, knock-out mice and transgenic mice are being produced.

Provides a centralized service to efficiently produce transgenic mice for basic research. At the University of Pennyslyvania.

This state-of-the art facility, supported by the Sealy Center for Cancer Cell Biology, is available for use by all UTMB scientists.

The Transgenic Mouse Core Facility of the University of Virginia (TMCF) provides centralized, expert service to efficiently produce transgenic and knockout mice for basic research for investigators at UVa.

Transgenic Mouse/ES Cell shared resource at The Vanderbilt-Ingram Cancer Center.

Transgenics and Gene Knockout - Wadsworth Center Core Facilities, New York State Department of Health.

Produces transgenic and knock out mice for cancer center members and members of the Yale community.