Located in Waltham, Massachusetts. Over sixty specialized collections are grouped into four broad categories (Judaica, history, literature, and creative arts) and include significant holdings on Louis D. Brandeis, Benjamin Disraeli, Leonardo da Vinci, Albert Einstein, and Yiddish Sheet Music, among others. Research affiliations: Center for Research Libraries, Research Library Group.

Houses Brandeis University's outstanding collection of modern and contemporary New England art.