Off the Beat
Humorous strip written and drawn by Emily K, about kids involved with band and music.
Off the Mark
Mark Parisi's daily comic panel is on the web with a daily cartoon, archives according to subject, some stuff to buy and syndication information.
Old Motherboard's Tranquillity Haven
Computer-related comics, cartoons and general humor by Roger Penwill.
Onion Head Monster
Strange comics and animations about this misunderstood monster. By Paul Friedrich.
Order of the Stick
Fantasy role playing oriented strip - includes cast of characters and some game design articles.
Orneryboy by Michael Lalonde
A comic strip about the adventures of a really moody boy and his perky girlfriend.
Orval
Orval the pig is the star of this comic strip which runs weekly in the Arkansas Times. Politics and culture are lampooned.
OsigmaComics
Features webcomic about a school in the UK featuring all the stereotypical characters and situations like world domination.
Otaku Life
An online comic strip about the secret life of college students and anime freaks. By Jeanette Brown.
Otter Girl
Comix featuring Otter Girl by Emma Stone. Also: Flash animation and a rainy day clipping project.
Out of My Mind
Regular comics, editorial cartoons and Web-A-Toons (web-only cartoons using animated gifs, and backgrounds) by Vikram Madan.
Over The Edge
Daily Web panel cartoon by Dan Reynolds. With selected past cartoons archived, and originals, cards and t-shirts to buy.
Ozy and Millie
Two young foxes endure the trials and tribulations of childhood.
Spoil Sports
Sports cartoons by Dominic Nunziato. A sports column in every cartoon.
The Outer Burrows
Surreal humor strip using found images, by Atrowbri and Zillno.